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About Lynch Syndrome

Lynch syndrome is a genetic condition that is diagnosed when a pathogenic variant in one of five genes (MLHL1, MSH2, MSH6, PMS2, and EPCAM) affects the normal growth and function of a cell. Individuals with Lynch syndrome are at increased risk for developing certain cancers.

Cancer risks associated with Lynch syndrome include:

Cancer Screening and Risk Reduction for Lynch Syndrome

Understanding your risk for developing cancer as well as the options available to you for prevention, early detection, and treatment can help improve your quality of life. Clinical management guidelines for surveillance and risk-reduction strategies differ from person to person and should involve a shared decision between you and your healthcare provider who takes into account risk factors specific to you. Recommendations may include:

Men and Women

  • Screening for colon and other gastrointestinal cancers, beginning between the ages of 20 and 25 or 30 and 35 (depending on the gene) and repeating every 2-5 years
  • Annual physical/neurological exam, beginning between the ages of 25 and 30
  • Annual urine analysis, beginning between the ages of 25 and 30


  • Considering surgery to remove the uterus, ovaries, and fallopian tubes (after childbearing age)*

*For more information about UT Health Austin’s Cancer Fertility Preservation service, please visit here

Treating Lynch Syndrome at UT Health Austin

Our genetic counselors help patients understand the benefits, limitations, and risks associated with undergoing genetic testing as well as how genetic testing affects healthcare management so that they can make informed decisions about their health. When discussing test results, our genetic counselors will work with you to develop a cancer screening plan specific to your needs.

Through our Multidisciplinary Case Conferences, we collaborate with our colleagues at The University of Texas at Austin and the Dell Medical School to stay informed of the latest research, diagnostic, and surveillance techniques, and we partner with existing providers in the Austin area to ensure we can successfully connect you with services recommended as part of your personalized cancer screening plan. We also provide you with community resources and help coordinate high-risk surveillance so that you have support every step of the way.

Care Team Approach

At UT Health Austin, we take a multidisciplinary approach to your care. This means you will benefit from the expertise of multiple specialists across a variety of disciplines caring for you in one place to avoid having to schedule multiple appointments with providers at locations all over the city. The Hereditary Cancer Screening and Risk Reduction care team includes clinical genetic counselors, medical oncologists, surgical oncologists, nurses, advanced practice providers, dietitians, social workers, and more as well as other members of the CaLM Care Team, who work together to help you get back to the things in your life that matter most to you. We also work alongside specialists across Cancer Fertility Preservation, Digestive Health, Women’s Health, Primary Care, Dermatology, and more.

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Hereditary Cancer Screening and Risk Reduction

Health Transformation Building, 8th Floor
1601 Trinity Street, Bldg. A, Austin, TX 78712
1-833-UT-CARES (1-833-882-2737)
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